Clobetasol Propionate
 
Product Name: Clobetasol Propionate
Synonyms: Clobetasol 17-Propionate.
Chemical Name: [17-(2'-chloroacetyl)- 9-fluoro-11-hydroxy-10,13,16-trimethyl- 3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Molecular formula: C25H32FO5
Molecular Weight: 466.97 g/mol
Melting Point: 195.5-197 C
Boiling Point.: 569 C at 760 mmHg
CAS No.: 25122-46-7
Specification Compliance: I.P/ B.P/U.S.P
Form: White to cream crystalline Powder odourless
 
Clobetasol Propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak.It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules).[2]

Applications:
  • Clobetasol propionate is used to help reduce the redness and itchiness of certain skin and scalp problems. These skin problems include eczema, psoriasis, dermatitis and neurodermatitis that have not responded to milder steroid creams or ointments, lotions or scalp applications.
  • Used as first-line treatment for both acute and chronic Graft vs Host disease of skin (associated with stem cell and bone marrow transplant).
  • It is used to treat skin and scalp conditions that have not been effectively treated with other steroids.
  • Used to treat skin problems caused by stress or other psychological factors.


 
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